I believe Persuasion, Deception, and UtF are easily the most common "skill vs. defense" rolls out there. I'll admit most of the problems come with UtF because many of the other applications normally have some kind of "floating target" that can make the attempt less certain in hostile situations. Some adjustments may need to be made for the common skills.
Deception: An interesting skill as the are a lot of times you'd be rolling this skill and comparing it against both an opposed Perception Check (for Appearance) and WILL Defense (for Information.) This is interesting because RAW against a low level non-heroic who is trained in Perception you could easily pass off information with a total roll of 12 while he easily sees through the appearance by using "take 10." Under the RAW an outrageous appearance is very likely be seen through but for someone highly skilled in deception passing off outrageous information may not be that challenging when even a -20 penalty to a skill still leaves a weak mind easily overcome.
Trying to Improve Access with Use Computer is a LOT like trying to Change Attitude with Persuasion and the two really should mimic each other. A thing to consider here is that living things can easily have a better WILL save than most computers IF you follow that a computer's WILL save is just 10 + INT modifier. I know you see higher WILL Defenses listed but you may find yourself asking how.
When it comes to shutting down an unwilling droid using Mechanics I believe the SAM will be highly appropriate. Granted most battle droids should have locked-access to prevent that you are essentially looking at a "one hit kill" which I don't believe should be too easy to pull off.